We are developing methods for reliable and efficient encoding, random access,
and decoding of digital data stored in DNA. We are also developing a fully
automated whole system architecture.
As part of this research we have been encoded many cool data items such as a
video from the OK Go band, books from Project Gutenberg, the Universal
Declaration of Human Rights, archival quality songs from the UNESCO Heritage
Montreux Jazz Archive, etc. Please let us know if you
have ideas for interesting and relevant data items!
February 22, 2022
Combinatorial PCR paper published in ACS Synth Bio, demonstrating a viable path for scaling up DNA data storage systems.
Our paper comparing various ways to preserve synthetic DNA is now published in Small Methods! Do you have DNA you’d like to store for long amounts of time? Is your freezer overflowing with DNA you might never use again, but want to keep just in case? We compare various commercial DNA preservation methods as well as some in-house methods to find half-lives, error rates, density and ease of use so you can decide what preservation method works best for you.
November 03, 2020
Our molecular tagging system, Porcupine, is now published in Nature Comms! Our DNA-based tags can be assembled with minimal lab resources (4+ billion possible tags!), applied onto the surface of physical objects that you want to track, and are decodable with a portable nanopore sensor in just a few seconds.
June 29, 2020
Our latest paper is out! Reading and writing in DNA data storage involves synthesizing and manipulating large pools of DNA molecules with (often) uneven distribution. We go deep on that in this paper!