MISL: DNA Storage Architecture and Methods

We are developing methods for reliable and efficient encoding, random access, and decoding of digital data stored in DNA. We are also developing a fully automated whole system architecture.

As part of this research we have been encoded many cool data items such as a video from the OK Go band, books from Project Gutenberg, the Universal Declaration of Human Rights, archival quality songs from the UNESCO Heritage Montreux Jazz Archive, etc. Please let us know if you have ideas for interesting and relevant data items!

News

February 09, 2023
MP3-seq preprint from Seelig group out now on bioRxiv.
July 27, 2022
With collaborators at UCSF and Harvard, we helped develop a “Retro-Cascorder” that records the order of gene expression in cells. Read about it in our newest paper published in Nature.
February 22, 2022
Combinatorial PCR paper published in ACS Synth Bio, demonstrating a viable path for scaling up DNA data storage systems.
September 01, 2021
MISL is a proud member of the DNA data storage alliance! DNA data storage is becoming real!
January 25, 2021
Our paper comparing various ways to preserve synthetic DNA is now published in Small Methods! Do you have DNA you’d like to store for long amounts of time? Is your freezer overflowing with DNA you might never use again, but want to keep just in case? We compare various commercial DNA preservation methods as well as some in-house methods to find half-lives, error rates, density and ease of use so you can decide what preservation method works best for you.

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