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• August 31, 2023
  MISLers are heading to DNA29: Congratulations to professor Georg Seelig for winning the Rozenberg Tulip Award! Also look out for Chandler, Sam, Cady, Carina, and Gwen in Sendai, Japan on Sept 11th-15th
• March 29, 2023
  Congratulations to MISL graduate students Carina Imburgia and Lancelot Wathieu on securing NSF GRFP awards, and MISL undergraduate researcher Kyvalya Reddy on receiving a Mary Gates Research Scholarship!
• February 09, 2023
  MP3-seq preprint from Seelig group out now on bioRxiv.
• January 28, 2023
  New preprint from MISL students and collaborators out on bioRxiv: “Design of stimulus-responsive two-state hinge proteins”
• July 27, 2022
  With collaborators at UCSF and Harvard, we helped develop a “Retro-Cascorder” that records the order of gene expression in cells. Read about it in our newest paper published in Nature.
• April 01, 2022
  Doctoring Direct-to-Consumer Genetic Tests preprint published in Biorxiv, exploring data integrity issues and doctorability of Direct-to-consumer genetic tests
• February 22, 2022
  Combinatorial PCR paper published in ACS Synth Bio, demonstrating a viable path for scaling up DNA data storage systems.
• December 15, 2021
  
  MISL awarded for laboratory safety and recognized for innovation in chemical hygiene practices.
• December 01, 2021
  MISL has achieved record breaking DNA synthesis density! Read about it in our latest paper, Toward nanoscale DNA writers: Unlocking scalable DNA data writing technology out now, and in the Microsoft blog post.
• September 24, 2021
  Check out our review on protein sequence analysis using nanopore sensors in Cell iScience
• September 01, 2021
  MISL is a proud member of the DNA data storage alliance! DNA data storage is becoming real!
• August 20, 2021
  NanoporeTERs are covered by GenomeWeb! Prof. Jeff Nivala is quoted. New Protein Reporters for MinIon Sequencer Point Toward Route for Single-Molecule Proteomics
• August 12, 2021
  NanoporeTERs paper is published in Nature Biotechnology! NanoporeTERs enable more direct monitoring of intra-cellular activity with a mix of synthetic biology, nanopore sensing, and machine learning. So many possibilities in sensing, better data for ML, etc. Check out a nice UW Allen School news article about the work :)
• August 06, 2021
  DNA-based similarity search paper is published in Nature Communications! Check-out a nice Allen School News post!
• April 22, 2021
  PurpleDrop version 6.1 is officially released with support for USB, software-controlled drive voltage, and capacitance-based volume sensing.
• February 19, 2021
  Professor Chris Thachuk’s latest paper entitled Absolute and arbitrary orientation of single-molecule shapes is now published in Science! This work describes a “moon shaped” asymmetric DNA origami (that we think looks a lot like the Star Wars Death Star) that could be used to help direct self-assembly at the nano-scale.
• January 25, 2021
  Our paper comparing various ways to preserve synthetic DNA is now published in Small Methods! Do you have DNA you’d like to store for long amounts of time? Is your freezer overflowing with DNA you might never use again, but want to keep just in case? We compare various commercial DNA preservation methods as well as some in-house methods to find half-lives, error rates, density and ease of use so you can decide what preservation method works best for you.
• November 03, 2020
  Our molecular tagging system, Porcupine, is now published in Nature Comms! Our DNA-based tags can be assembled with minimal lab resources (4+ billion possible tags!), applied onto the surface of physical objects that you want to track, and are decodable with a portable nanopore sensor in just a few seconds.
• June 29, 2020
  Our latest paper is out! Reading and writing in DNA data storage involves synthesizing and manipulating large pools of DNA molecules with (often) uneven distribution. We go deep on that in this paper!
• June 14, 2020
  Karin and Luis have earned the ACM SIGARCH Maurice Wilkes Award for their career contributions to DNA-based digital data storage! Congrats Karin and Luis!
• May 28, 2020
  Our latest preprint showcases our technique for augmenting DNA data storage with the ability to perform similarity search over a database with millions of images!
• April 08, 2020
  Katie was interviewed for a podcast about Porcupine – Bioinformatics Chat by Roman Cheplyaka. The episode should be out by the end of the month!
• March 30, 2020
  Congratulations to Karen Zhang for the Goldwater Scholarship and David Wong for the Mary Gates Scholarship! Woo!
• March 08, 2020
  Check out our latest preprint on Porcupine, a molecular tagging system using DNA to tag physical objects and basecall-free nanopore signals for reading!
• December 24, 2019
  MISL is recognized for sustainability efforts in the UW Green Lab Spotlight.
• November 11, 2019
  Check out our latest preprint on NanoporeTERs, a new class of nanopore-addressable protein reporters for multiplexed detection of cellular outputs using commerically available nanopore sensor arrays!
• November 10, 2019
  Max gave an invited talk at ICCAD 2019 about Puddle! Check out the accompanying paper.
• July 03, 2019
  Check out our latest paper in Nature Communications that demonstrates a new assembly protocol, codec and read-until for DNA data storage using nanopores!
• May 24, 2019
  Katie gave a talk on molecular tagging at Oxford Nanopore’s London Calling 2019.
• May 22, 2019
  Jeff gave a talk on NanoporeTERs (nanopore-based reporter proteins) at Oxford Nanopore’s London Calling 2019.
• May 08, 2019
  Check out our review paper in Nature Genetics Reviews for a comprehensive view of the emerging field of DNA data storage.
• April 15, 2019
  The Allen School put together a nice news piece on some of our recent work in fluidics, including our ASPLOS and Nature Communications papers.
• April 12, 2019
  Check out our latest paper in Nature Communications that demonstrates high-density DNA storage on top of PurpleDrop!
• March 21, 2019
  Our paper demonstrating an end-to-end automated system for DNA data storage (including synthesis and sequencing!) appeared in Scientific Reports. The paper got some press coverage from GeekWire and a press release from Microsoft.
• March 14, 2019
  
  Bill Gates came by our fancy new lab during the dedication of the Allen School’s new building. And of course Luis went for a selfie! 📸
• March 01, 2019
  We made a quick video about Puddle and PurpleDrop, our microfluidics software and hardware. The video is a lightning talk summarizing our forthcoming ASPLOS 2019 presentation.
• January 01, 2019
  We put together a paper about our vision of a hybrid molecular-electronic computing platform that combines traditional silicon computing with DNA data storage and computing. It’s in the January 2019 issue of the Proceedings of the IEEE.
• November 07, 2018
  Our paper on Puddle and PurpleDrop was accepted to ASPLOS 2019. Check out the preprint!
• November 01, 2018
  Our poster on Puddle and PurpleDrop at the Allen School Affiliates program got runner-up for the Madrona Prize.
• October 11, 2018
  Our paper on content-addressable DNA databases wins best student paper award at DNA24. Woohoo! Take a look at the paper!
• September 27, 2018
  Our #MemoriesInDNA project will go to space! Submit your photo(s) here!
• August 20, 2018
  Our paper on content-addressable DNA databases demonstrating application-driven learning of DNA sequence encodings will appear this October in DNA24. Take a look at the paper!
• August 04, 2018
  
  Katie led a demo at the Pacific Science Center for their Meet a Scientist outreach program. Kids of all ages learned how to read and write sentences in a special DNA-like code!
• May 14, 2018
  Max gave a talk on programming languages and microfluidics at PNW PLSE.
• February 20, 2018
  
  Our paper detailing our adventure with large-scale DNA data storage was just published in Nature Biotechnology. Check it out!
  Update: We’re on the cover!
• February 11, 2018
  Max and gave a talk about Puddle at the Wild and Crazy Ideas session at ASPLOS 2018.
• January 24, 2018
  We just launched our #MemoriesInDNA project! Submit a photo to help us understand what sorts of images people want to remember. We’ll take a sample of these images and archive them into DNA. Check out the website for more!
• January 13, 2018
  Max and Jared gave a talk at OBT at POPL 2018. Check out the abstract or the project page.
• November 28, 2017
  Our NIPS paper on clustering for decoding digital data from DNA sequencing was just released. Enjoy! Clustering Billions of Reads for DNA Data Storage.
• November 18, 2017
  How DNA will solve our data storage problem, Cosmos Magazine
• October 05, 2017
  In 1,000 Years, This Recording Of Miles Davis Preserved In DNA Will Still Be Perfect, Fast Company
• October 04, 2017
  The internet (and all that jazz) can be stored in DNA, The Times
• August 10, 2017
  Scientists Hack a Computer Using DNA, MIT Technology Review
• March 14, 2017
  We just released a manuscript describing our last year or so of progress towards viable DNA data storage. Enjoy! Scaling up DNA data storage and random access retrieval.
• December 17, 2016
  Your Data Could Be Stored In DNA Within The Decade, KUOW On the Record
• December 04, 2016
  Encoding data in DNA for millennia? UW and Microsoft Research are on it, GeekWire
• August 05, 2016
  Why Microsoft stored 200MB of data in DNA strands, and what’s next, TechRepublic
• July 12, 2016
  How Our Own Genetic Code Could Make the Internet Last for Millennia, Future Tense
• July 11, 2016
  New record for storing digital data in DNA, Gizmag
• July 10, 2016

  200 MB in DNA

  MISL researchers have achieved a new milestone by encoding and retrieving a record-high 200 megabytes of data on DNA!
  Read more »
• July 08, 2016
  Microsoft And UW Store 200MB Using DNA Medium, Ubergizmo
• July 08, 2016
  Researchers store 200MB of data on molecular strands, SlashGear
• July 08, 2016
  Microsoft researchers claim major breakthrough in DNA data storage, SiliconANGLE
• July 08, 2016
  Scientists Fit Hundreds of Megabytes of Data onto DNA, Popular Mechanics
• July 08, 2016
  Microsoft Stores 200MB of Data on Strands of DNA, PC Magazine
• July 08, 2016
  Microsoft Writes ‘War and Peace’ Onto DNA, Newsweek
• July 08, 2016
  At UW, they encoded a music video and books onto DNA, KUOW
• July 08, 2016
  Microsoft And UW Researchers Set World Record Storing 200MB Of Data On A Single Strand Of DNA, Hot Hardware
• July 08, 2016
  The Thumb Drive Of The Future Is Made Of DNA, GOOD
• July 08, 2016
  The breakthrough that could mean your phone will never run out of space again: Microsoft sets DNA strand storage record, Daily Mail
• July 08, 2016
  Microsoft, university researchers break DNA data storage record, Computerworld
• July 08, 2016
  Microsoft, university researchers break DNA data storage record, ARNnet
• July 07, 2016
  Scientists successfully use DNA to store an OK Go music video, much more, Yahoo! Music
• July 07, 2016
  DNA Could Be the Future of Data Storage, U.S. News & World Report
• July 07, 2016
  Microsoft stored an OK Go music video in strings of DNA, The Verge
• July 07, 2016
  UW, Microsoft claim big breakthrough with data storage using DNA, The Seattle Times
• July 07, 2016
  New DNA ‘hard drive’ could keep files intact for millions of years, The Register
• July 07, 2016
  Microsoft Reports a Big Leap Forward for DNA Data Storage, MIT Technology Review
• July 07, 2016
  Researchers stored an OK Go music video on strands of DNA, Mashable
• July 07, 2016
  Microsoft Wants to Soare the Entire Internet on a DNA Strand, Inverse
• July 07, 2016
  Video in a test tube? Microsoft and UW raise the bar for DNA data storage systems, GeekWire
• July 07, 2016
  Microsoft wrote an OK Go music video to DNA, Engadget
• July 07, 2016
  Microsoft set a new record by storing an OK Go music video and the top 100 books ever written on strands of DNA, Business Insider
• May 31, 2016
  Tech Turns to Biology as Data Storage Needs Explode, Scientific American
• April 30, 2016
  Microsoft is Exploring DNA Data Storage, InformationWeek
• April 29, 2016
  Plugging Into DNA for Digital Data Storage, Science Friday
• April 29, 2016
  Microsoft Buys 10M DNA Molecules for Dense Storage Research, PC Magazine
• April 28, 2016
  Microsoft buys 10 million DNA molecules to try fitting today’s sprawling data vaults on a match head, ZDNet
• April 28, 2016
  Inspired by nature, UW Daily
• April 28, 2016
  Microsoft joins the drive to store data in DNA: Firm will buy millions of strands of synthetic genetic code for long-term storage, Daily Mail
• April 28, 2016
  Why Microsoft is buying 10 million strands of DNA, CBS News
• April 27, 2016
  Genetics startup Twist Bioscience is working with Microsoft to store the world’s data in DNA, TechCrunch
• April 27, 2016
  The new data center can be your DNA, proven in experiment by UW and Microsoft, International Business Times
• April 27, 2016
  Microsoft Buys Into DNA Data Storage, IEEE Spectrum
• April 27, 2016
  Microsoft is buying 10 million molecules of custom DNA from a San Francisco startup, Business Insider
• April 24, 2016
  Storing Digital Data in DNA, CBC Radio
• April 15, 2016
  DNA Storage Could Make Data Centers Obsolete, Newsweek
• April 13, 2016
  From data centers to sugar cubes: How UW, Microsoft are shrinking data storage space through DNA, Puget Sound Business Journal
• April 11, 2016
  Researchers store, search, retrieve images in DNA, CNET
• April 10, 2016
  Scientists Store, Retrieve Digital Images in DNA, Tech Times
• April 08, 2016
  Scientists Stored Digital Images Inside DNA, Then Retrieved Them, Motherboard
• April 08, 2016
  Scientists Stored These Images in DNA—Then Flawlessly Retrieved Them, Gizmodo
• April 08, 2016
  DNA Data Storage Moves Beyond Moore’s Law, Discover Magazine
• April 08, 2016
  Radical breakthrough stores digital pictures in DNA for first time - and could revolutionise computer storage, Daily Mail
• April 08, 2016
  It took a whole team of UW scientists to make this cute cat pic, Crosscut
• April 07, 2016
  LOL! Researchers store cat photo (and lots more digital data) in DNA molecules, GeekWire
• December 03, 2015
  Data Storage on DNA Can Keep It Safe for Centuries, The New York Times